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1-(2,4-difluorophenyl)guanidine hydrochloride

🥰Excellent
Catalog No. T50030Cas No. 112677-40-4

1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signaling, resulting in an analgesic effect.

1-(2,4-difluorophenyl)guanidine hydrochloride

1-(2,4-difluorophenyl)guanidine hydrochloride

🥰Excellent
Purity: 99.83%
Catalog No. T50030Cas No. 112677-40-4
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signaling, resulting in an analgesic effect.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$40In StockIn Stock
10 mg$58In StockIn Stock
25 mg$103In StockIn Stock
50 mg$153In StockIn Stock
100 mg$232In StockIn Stock
200 mg$347In StockIn Stock
1 mL x 10 mM (in DMSO)$41In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:99.83%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
1-(2,4-difluorophenyl)guanidine hydrochloride is a compound that is a potent and selective inhibitor of the voltage-gated sodium channel Nav1.7, a key player in pain signaling. It is therefore able to reduce pain signaling, resulting in an analgesic effect.
Chemical Properties
Molecular Weight207.61
FormulaC7H8ClF2N3
Cas No.112677-40-4
SmilesNC(NC1=CC=C(F)C=C1F)=N.[H]Cl
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 45 mg/mL (216.75 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.8167 mL24.0836 mL48.1672 mL240.8362 mL
5 mM0.9633 mL4.8167 mL9.6334 mL48.1672 mL
10 mM0.4817 mL2.4084 mL4.8167 mL24.0836 mL
20 mM0.2408 mL1.2042 mL2.4084 mL12.0418 mL
50 mM0.0963 mL0.4817 mL0.9633 mL4.8167 mL
100 mM0.0482 mL0.2408 mL0.4817 mL2.4084 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

1-(2,4-difluorophenyl)guanidine Hydrochloride1(2,4difluorophenyl)guanidine hydrochloride1 (2,4 difluorophenyl)guanidine hydrochloride
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