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C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), human acetate inhibits cAMP synthesis stimulated by histamine and 5-HT or directly by Forskolin.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $57 | In Stock | |
5 mg | $229 | In Stock | |
10 mg | $330 | In Stock | |
25 mg | $498 | In Stock | |
50 mg | $685 | In Stock | |
100 mg | $917 | In Stock | |
200 mg | $1,230 | In Stock |
Description | C-Type Natriuretic Peptide (CNP) (1-22), human acetate is an agonist of natriuretic peptide receptor B (NPR-B), an endothelial-derived relaxant and growth inhibitory factor. C-Type Natriuretic Peptide (CNP) (1-22), human acetate inhibits cAMP synthesis stimulated by histamine and 5-HT or directly by Forskolin. |
In vitro | In CHO cells expressing human NPR-B, C-Type Natriuretic Peptide (CNP) (1-22), human acetate (0.01, 0.1, 1, 10, 100, 1000 nM) increased cGMP production in a concentration-dependent manner[2]. |
In vivo | C-Type Natriuretic Peptide (CNP) (1-22), human acetate (2 nM; i.c.v.) induced an increase in the severity of picrotoxin-kindled convulsions 24 hours after application of the peptide[3]. |
Synonyms | C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base) |
Molecular Weight | 2371.68 |
Formula | C97H162F3N27O32S3 |
Smiles | CC(O)=O.FC(F)(F)C(O)=O.O=C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1=O)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CC(O)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)[C@](NC([C@H](CSSC[C@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CO)N1)=O)CCSC)=O)CO)=O)=O)CC(C)C)=O)=O)C(O)=O)NC(CNC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(C)C)NC(CN)=O)=O)=O)=O)=O)=O)([H])CC2=CC=CC=C2 |
Sequence | Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys |
Sequence Short | GLSKGCFGLKLDRIGSMSGLGC |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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