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Anti-NKp46/NCR1 Polyclonal Antibody
(Synonyms: NKP46FLJ99094, NKp46, NCR1, MAR-1, Ly94, CD335) Copy Product Info
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Synonyms: NKP46FLJ99094, NKp46, NCR1, MAR-1, Ly94, CD335
Catalog No. TMAB-01241 Copy Product Info
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Anti-NKp46/NCR1 Polyclonal Antibody is a Rabbit antibody targeting NKp46/NCR1. Anti-NKp46/NCR1 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Anti-NKp46/NCR1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-NKp46/NCR1 Polyclonal Antibody is a Rabbit antibody targeting NKp46/NCR1. Anti-NKp46/NCR1 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | NKP46FLJ99094, NKp46, NCR1, MAR-1, Ly94, CD335 |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | Selectively expressed by both resting and activated NK cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |
| Immunogen | KLH conjugated synthetic peptide: human NCR1 |
| Antigen Species | Human |
| Gene Name | NCR1 |
| Gene ID | |
| Protein Name | Natural cytotoxicity triggering receptor 1 |
| Uniprot ID | |
| Biology Area | Cytotoxic Cells,Transmembrane |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Molecular Weight | Theoretical: 31 kDa. Actual: 46 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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