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Anti-SCN10A/Nav1.8 Polyclonal Antibody
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Catalog No. TMAB-01668
Anti-SCN10A/Nav1.8 Polyclonal Antibody is a Rabbit antibody targeting SCN10A/Nav1.8. Anti-SCN10A/Nav1.8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-SCN10A/Nav1.8 Polyclonal Antibody
Anti-SCN10A/Nav1.8 Polyclonal Antibody
😃Good
Catalog No. TMAB-01668
Anti-SCN10A/Nav1.8 Polyclonal Antibody is a Rabbit antibody targeting SCN10A/Nav1.8. Anti-SCN10A/Nav1.8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SCN10A/Nav1.8 Polyclonal Antibody is a Rabbit antibody targeting SCN10A/Nav1.8. Anti-SCN10A/Nav1.8 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Pig,Cow) |
| Verified Activity | 1. Tissue/cell: rat spinal cord; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-SCN10A Polyclonal Antibody, Unconjugated (TMAB-01668) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Tissue/cell: rat brain tissue;4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-SCN10A Polyclonal Antibody, Unconjugated (TMAB-01668) 1:200, overnight at 4°C; The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. |
| Application | IHC-P,IHC-Fr,IF |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. Note=It can be translocated to the extracellular membrane through association with S100A10. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Nav1.8 protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, Nav1.8 forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Nav1.8 plays a role in neuropathic pain mechanisms. |
| Immunogen | KLH conjugated synthetic peptide: human SCN10A/NAV1.8 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Sodium Channels,Nociception |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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