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Anti-LAMP2 Antibody (2T557) is a Rabbit antibody targeting LAMP2. Anti-LAMP2 Antibody (2T557) can be used in WB,IHC,IP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-LAMP2 Antibody (2T557) is a Rabbit antibody targeting LAMP2. Anti-LAMP2 Antibody (2T557) can be used in WB,IHC,IP. |
Synonyms | lysosomal-associated membrane protein 2, LGP110, LAMPB, LAMP-2, CD107b |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of LAMP2a on different lysates using anti-LAMP2a antibody at 1/1,000 dilution. Positive control: Lane 1: Human placenta, Lane 2: JAR, Lane 3: Human liver. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-LAMP2a antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LAMP2a antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-LAMP2a antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-LAMP2a antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse placenta tissue using anti-LAMP2a antibody. Counter stained with hematoxylin. 7. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-LAMP2a antibody. Counter stained with hematoxylin. |
Application | |
Recommended Dose | WB: 1:1000-5000; IHC: 1:50-200 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Lysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-1 (also designated CD107A) and LAMP-2 (also designated CD107B) are involved in a variety of functions, including cellular adhesion, and are thought to participate in the process of tumor invasion and metastasis. Newly synthesized LAMP-1 and LAMP-2 proteins are sorted at the trans Golgi network and are transported intracellularly via a pathway that is distinct from the clathrin-coated vesicles used for the mannose-6 phosphate receptor. LAMP-1 is expressed on the surface of thrombin-activated but not resting platelets, and it is thought to be involved in the adhesive, prothrombic properties of these cells. Both LAMP-1 and LAMP-2 are involved in maintaining lysosome acidity and protecting the lysosomal membranes from autodigestion, and their expression is increased in patients with lysosomal storage disorders. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 120 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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