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N-Nitrosomorpholine

Name: N-Nitrosomorpholine
Brand: TargetMol
SKU: T40684
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40684Cas No. 59-89-2

N-Nitrosomorpholine is a light-sensitive nitrosamine with strong carcinogenicity in animals and is commonly used to induce liver cancer models.

N-Nitrosomorpholine

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Catalog No. T40684Cas No. 59-89-2

N-Nitrosomorpholine is a light-sensitive nitrosamine with strong carcinogenicity in animals and is commonly used to induce liver cancer models.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
500 mg	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:≥98%

Appearance:Viscous

Color:Yellow

Resource Download

COA HNMR

Product Introduction

N-Nitrosomorpholine AI Summary

N-Nitrosomorpholine affects various blood parameters such as red blood cell count, hemoglobin levels, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, platelet count, and white blood cell count. It also impacts the percentage of different types of white blood cells including neutrophils, eosinophils, basophils, monocytes, and lymphocytes. Additionally, this compound influences levels of albumin, alkaline phosphatase, cholesterol, triglycerides, phospholipids, bilirubin, blood urea nitrogen, aspartate transaminase, creatinine, sodium, potassium, chloride, calcium, phosphorus, protein, alanine transaminase, lactate dehydrogenase, and gamma-glutamyl transferase. Furthermore, it impact body weight during the study..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

N-Nitrosomorpholine is a light-sensitive nitrosamine with strong carcinogenicity in animals and is commonly used to induce liver cancer models.

Chemical Properties

Molecular Weight	116.12
Formula	C₄H₈N₂O₂
Cas No.	59-89-2
Smiles	O=NN1CCOCC1
Relative Density.	1.2829 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 98 mg/mL (843.95 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (28.42 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	8.6118 mL	43.0589 mL	86.1178 mL	430.5890 mL
5 mM	1.7224 mL	8.6118 mL	17.2236 mL	86.1178 mL
10 mM	0.8612 mL	4.3059 mL	8.6118 mL	43.0589 mL
20 mM	0.4306 mL	2.1529 mL	4.3059 mL	21.5295 mL
50 mM	0.1722 mL	0.8612 mL	1.7224 mL	8.6118 mL
100 mM	0.0861 mL	0.4306 mL	0.8612 mL	4.3059 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc