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Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody (Synonyms: p-IGF1R/CD221 (Y1280), p-IGF1R/CD221 (Tyr1280...)
Catalog No. TMAC-02096 Copy Product Info
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Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IGF1R/CD221 (Tyr1280). Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody can be used in WB.
Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-02096
Synonyms p-IGF1R/CD221 (Y1280), p-IGF1R/CD221 (Tyr1280), IGF1R/CD221 (p-Y1280), IGF1R/CD221 (p-Tyr1280)
Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IGF1R/CD221 (Tyr1280). Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody can be used in WB.
Anti-Phospho-IGF1R/CD221
(Tyr1280) Polyclonal Antibody
(Tyr1280) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IGF1R/CD221 (Tyr1280). Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody can be used in WB. |
| Synonyms | p-IGF1R/CD221 (Y1280), p-IGF1R/CD221 (Tyr1280), IGF1R/CD221 (p-Y1280), IGF1R/CD221 (p-Tyr1280) |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of extract from 293 cells using IGF-1R (Phospho-Tyr1280) Antibody TMAC-02096.  |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. Ref.19 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, Ref.21 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 1280 (S-F-Y(p)-Y-S) derived from Human IGF-1R |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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