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4,4-Dimethyl-2-cyclopenten-1-one, derived from Apocyniveneti Folium, exhibits enhanced tumor-specific cytotoxicity [1].


| Description | 4,4-Dimethyl-2-cyclopenten-1-one, derived from Apocyniveneti Folium, exhibits enhanced tumor-specific cytotoxicity [1]. |
| In vitro | 4,4-Dimethyl-2-cyclopenten-1-one exhibits selective cytotoxicity towards tumor cells, particularly HSC-2 and HL-60, with CC50 values of 43.8 μg/mL for HSC-2, 152 μg/mL for HSC-3, 118 μg/mL for HSG, 14.0 μg/mL for HL-60, 177 μg/mL for HGF, and 123 μg/mL for normal cells (HPC) [1]. |
| Synonyms | 4,4-Dimethylcyclopent-2-enone |
| Molecular Weight | 110.15 |
| Formula | C7H10O |
| Cas No. | 22748-16-9 |
| Smiles | O=C1C=CC(C)(C)C1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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