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Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.60 kDa and the accession number is G7Q0B0.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $172 | 7-10 days | 7-10 days | |
| 10 μg | $286 | 7-10 days | 7-10 days | |
| 20 μg | $478 | 7-10 days | 7-10 days | |
| 50 μg | $957 | 7-10 days | 7-10 days | |
| 100 μg | $1,620 | 7-10 days | 7-10 days | |
| 200 μg | $2,930 | 7-10 days | 7-10 days | |
| 500 μg | $6,520 | 7-10 days | 7-10 days |
| Biological Activity | 1. Immobilized Cynomolgus Claudin 6 VLP at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 4ng/ml determined by ELISA (QC Test).
2. Cynomolgus Claudin 6 VLP immobilized on CM5 Chip can bind Anti-Claudin 6 Antibody with an affinity constant of 0.85 nM as determined in SPR assay. |
| Description | Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.60 kDa and the accession number is G7Q0B0. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Accession Number | G7Q0B0 |
| Synonyms | Skullin 2,Skullin,EGM_11390,CLDN6,Claudin-6,Claudin6,Claudin |
| Construction | Met1-Val220 |
| Protein Purity | > 95% as determined by HPLC |
| Molecular Weight | 24.60 kDa (predicted) |
| Endotoxin | < 1 EU/μg by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant. |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. |
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