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2-Amino-2-methyl-1-propanol

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Catalog No. TSH-00015Cas No. 124-68-5

2-Amino-2-methyl-1-propanol (AMP) is an emulsifier, pH buffer, and surfactant used to prepare solutions with a pH of 8.7–10.4, exhibiting inhibitory effects against Plasmodium falciparum.

2-Amino-2-methyl-1-propanol
Other Forms of 2-Amino-2-methyl-1-propanol:
2-Amino-2-Methyl-1-Propanol HydrochlorideTSH-002213207-12-3
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2-Amino-2-methyl-1-propanol

🥰Excellent
Catalog No. TSH-00015Cas No. 124-68-5
2-Amino-2-methyl-1-propanol (AMP) is an emulsifier, pH buffer, and surfactant used to prepare solutions with a pH of 8.7–10.4, exhibiting inhibitory effects against Plasmodium falciparum.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 g$29-In Stock
250 g$40-In Stock
500 g$53-In Stock
1 mL x 10 mM (in DMSO)$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
2-Amino-2-methyl-1-propanol (AMP) is an emulsifier, pH buffer, and surfactant used to prepare solutions with a pH of 8.7–10.4, exhibiting inhibitory effects against Plasmodium falciparum.
In vivo
Methods:
Rats were orally administered 2-Amino-2-methyl-1-propanol at doses ranging from 1100 to 1700 mg/kg for 30 consecutive days.
Results:
Some rats exhibited elevated serum levels of SGPT (serum glutamate pyruvate transaminase) and OCT (ornithine carbamoyltransferase), but no significant gross pathological or histopathological changes were observed.[4]
Chemical Properties
Molecular Weight89.14
FormulaC4H11NO
Cas No.124-68-5
SmilesOCC(N)(C)C
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight | store at 4°C
Solubility Information
DMSO: 80 mg/mL (897.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM11.2183 mL56.0915 mL112.1831 mL560.9154 mL
5 mM2.2437 mL11.2183 mL22.4366 mL112.1831 mL
10 mM1.1218 mL5.6092 mL11.2183 mL56.0915 mL
20 mM0.5609 mL2.8046 mL5.6092 mL28.0458 mL
50 mM0.2244 mL1.1218 mL2.2437 mL11.2183 mL
100 mM0.1122 mL0.5609 mL1.1218 mL5.6092 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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