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trans-4,5-epoxy-2(E)-Decenal

Name: trans-4,5-epoxy-2(E)-Decenal
Brand: TargetMol
SKU: T36508
Rating: 4.5 (1 reviews)

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Catalog No. T36508Cas No. 134454-31-2

Alias trans-4,5-epoxy-2(E)-Decenal, 3-(3-pentyloxiranyl)-2E-propenal

Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of decomposed lipids, with a detection threshold of 1.5 pg/l in air.[1] trans-4,5-epoxy-2(E)-Decenal also reacts with nucleophiles (lysine amino groups) on proteins, leading to loss of cell function and viability.[2] This reactive aldehyde is therefore a useful tool in elucidating the effects of peroxidative damage in experimental models.

trans-4,5-epoxy-2(E)-Decenal

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Catalog No. T36508Alias trans-4,5-epoxy-2(E)-Decenal, 3-(3-pentyloxiranyl)-2E-propenalCas No. 134454-31-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$736	35 days	35 days
5 mg	$3,180	35 days	35 days
10 mg	$5,620	35 days	35 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Synonyms

trans-4,5-epoxy-2(E)-Decenal, 3-(3-pentyloxiranyl)-2E-propenal

Chemical Properties

Molecular Weight	168.236
Formula	C₁₀H₁₆O₂
Cas No.	134454-31-2
Smiles	CCCCC[C@@H]1O[C@H]1\C=C\C=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMF: 30 mg/mL (178.32 mM), Sonication is recommended.

Ethanol: 30 mg/mL (178.32 mM), Sonication is recommended.

DMSO: 30 mg/mL (178.32 mM), Sonication is recommended.

Solution Preparation Table

DMF/Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9440 mL	29.7202 mL	59.4403 mL	297.2016 mL
5 mM	1.1888 mL	5.9440 mL	11.8881 mL	59.4403 mL
10 mM	0.5944 mL	2.9720 mL	5.9440 mL	29.7202 mL
20 mM	0.2972 mL	1.4860 mL	2.9720 mL	14.8601 mL
50 mM	0.1189 mL	0.5944 mL	1.1888 mL	5.9440 mL
100 mM	0.0594 mL	0.2972 mL	0.5944 mL	2.9720 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc