GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

Name: GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00356
Rating: 4.5 (1 reviews)

(Synonyms: Somatotropin receptor, serum binding protein, growth hormone receptor, growth hormone binding protein, GHR, GHBP, GH receptor) Copy Product Info

Synonyms: Somatotropin receptor, serum binding protein, growth hormone receptor, growth hormone binding protein, GHR, GHBP, GH receptor

Catalog No. TMPJ-00356 Copy Product Info

Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	7-10 days	7-10 days
10 µg	$91	7-10 days	7-10 days
20 µg	$133	7-10 days	7-10 days
50 µg	$222	7-10 days	7-10 days
100 µg	$397	7-10 days	7-10 days
200 µg	$715	7-10 days	7-10 days
500 µg	$1,570	7-10 days	7-10 days
1 mg	$2,230	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q3UP14
Amino Acid	Met1-Gln273
Construction	Met1-Gln273
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Somatotropin receptor, serum binding protein, growth hormone receptor, growth hormone binding protein, GHR, GHBP, GH receptor
Research Background	Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

Chemical Properties

Molecular Weight

65-90 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) chemical structure | GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) molecular weight