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Serpin H1 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00995
Synonyms: Arsenic-Transactivated Protein 3, SERPINH2, Rheumatoid Arthritis-Related Antigen RA-A47, HSP47, Collagen-Binding Protein, CBP1, AsTP3, SERPINH1, 47 kDa Heat Shock Protein, Serpin H1, Cell Proliferation-Inducing Gene 14 Protein, Colligin, CBP2

Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Serpin H1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number P50454
Synonyms Arsenic-Transactivated Protein 3, SERPINH2, Rheumatoid Arthritis-Related Antigen RA-A47, HSP47, Collagen-Binding Protein, CBP1, AsTP3, SERPINH1, 47 kDa Heat Shock Protein, Serpin H1, Cell Proliferation-Inducing Gene 14 Protein, Colligin, CBP2
Amino Acid Ala19-Leu418
Construction Recombinant Human Serine Protease Inhibitor-clade H1 is produced by our Mammalian expression system and the target gene encoding Ala19-Leu418 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 51 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes.

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Keywords

Serpin H1 Protein, Human, Recombinant (His) SERPINH-1 Arsenic-Transactivated Protein 3 SERPINH2 SERPINH 1 CBP-1 Rheumatoid Arthritis-Related Antigen RA-A47 SERPINH-2 HSP47 CBP-2 Collagen-Binding Protein CBP 1 HSP-47 CBP1 SERPINH 2 AsTP3 SERPINH1 47 kDa Heat Shock Protein Serpin H1 HSP 47 CBP 2 Cell Proliferation-Inducing Gene 14 Protein Colligin CBP2 recombinant recombinant-proteins proteins protein

 

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