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UBE2D1 Protein, Human, Recombinant (GST)

Catalog No. TMPJ-00999
Synonyms: Ubiquitin-conjugating enzyme E2(17)KB 1, UB, UbcH5, UBC5A, Stimulator of Fe transport, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2-17 kDa 1, UBC4/5 homolog, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1, SFT

Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

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UBE2D1 Protein, Human, Recombinant (GST)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 28.00
50 μg 5 days $ 104.00
500 μg 5 days $ 434.00
1 mg 5 days $ 621.00
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Biological Description
Technical Params
Product Properties
Description Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Species Human
Expression System E. coli
Tag N-GST
Accession Number P51668
Synonyms Ubiquitin-conjugating enzyme E2(17)KB 1, UB, UbcH5, UBC5A, Stimulator of Fe transport, Ubiquitin carrier protein D1, Ubiquitin-conjugating enzyme E2-17 kDa 1, UBC4/5 homolog, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-protein ligase D1, SFT
Amino Acid Met1-Met147
Construction Recombinant Human Ubiquitin-conjugating Enzyme E2 D1 is produced by our E.coli expression system and the target gene encoding Met1-Met147 is expressed with a GST tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 40 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

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Keywords

UBE2D1 Protein, Human, Recombinant (GST) Ubiquitin-conjugating enzyme E2(17)KB 1 UB UbcH5 UBC5A Stimulator of Fe transport Ubiquitin carrier protein D1 Ubiquitin-conjugating enzyme E2-17 kDa 1 UBC4/5 homolog Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-protein ligase D1 SFT recombinant recombinant-proteins proteins protein

 

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