Shopping Cart

Remove All
Your shopping cart is currently empty

Scopolamine

Name: Scopolamine
Brand: TargetMol
SKU: T3S0478
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T3S0478Cas No. 51-34-3

Alias Skopolamin, Scopine tropate, Scopine (-)-tropate, Hyoscine

1. Scopolamine (Scopine (-)-tropate), a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity. 2. Scopolamine can increase acetylcholinesterase activity by was significantly attenuated by RCM treatment. 3. Scopolamine can cause learning and memory impairments and galantamine can reverse the symptom. 4. Scopolamine produces rapid and significant symptom improvement in patients with depression.

Scopolamine

🥰Excellent

Purity: 99.95%

Catalog No. T3S0478Alias Skopolamin, Scopine tropate, Scopine (-)-tropate, HyoscineCas No. 51-34-3

Product information is being updated, if you want to purchase, please click the bulk custom button.

Bulk & Custom

Questions

Batch Information

Select Batch

Purity:99.95%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	1. Scopolamine (Scopine (-)-tropate), a nonselective muscarinic receptor antagonist, induces distinct behaviors of attenuated motility and C-like hyperactivity. 2. Scopolamine can increase acetylcholinesterase activity by was significantly attenuated by RCM treatment. 3. Scopolamine can cause learning and memory impairments and galantamine can reverse the symptom. 4. Scopolamine produces rapid and significant symptom improvement in patients with depression.
Targets&IC50	5-HT3:2.09 μM.
Alias	Skopolamin, Scopine tropate, Scopine (-)-tropate, Hyoscine

Chemical Properties

Molecular Weight	303.35
Formula	C₁₇H₂₁NO₄
Cas No.	51-34-3
Smiles	CN1[C@H]2C[C@@H](C[C@@H]1[C@H]1O[C@@H]21)OC(=O)[C@H](CO)c1ccccc1
Relative Density.	1.31

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 75 mg/mL (247.24 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2965 mL	16.4826 mL	32.9652 mL	164.8261 mL
5 mM	0.6593 mL	3.2965 mL	6.5930 mL	32.9652 mL
10 mM	0.3297 mL	1.6483 mL	3.2965 mL	16.4826 mL
20 mM	0.1648 mL	0.8241 mL	1.6483 mL	8.2413 mL
50 mM	0.0659 mL	0.3297 mL	0.6593 mL	3.2965 mL
100 mM	0.0330 mL	0.1648 mL	0.3297 mL	1.6483 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc