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Rhodojaponin II

Name: Rhodojaponin II
Brand: TargetMol
SKU: T5S0526
Price: 170 USD
Availability: InStock
Rating: 5 (10 reviews)

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🥰Excellent

Catalog No. T5S0526Cas No. 26116-89-2

1. Rhodojaponin II correlates pretty well with cardiotoxicity.

Rhodojaponin II

Copy Product Info

🥰Excellent

Purity: 99.92%

Catalog No. T5S0526Cas No. 26116-89-2

1. Rhodojaponin II correlates pretty well with cardiotoxicity.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$38	In Stock	In Stock
5 mg	$68	In Stock	In Stock
10 mg	$101	In Stock	In Stock
25 mg	$170	In Stock	In Stock
50 mg	Preferential	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.92%

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Rhodojaponin II AI Summary

Rhodojaponin II shows significant anti-inflammatory activity in mouse RAW264.7 cells by inhibiting LPS-induced nitric oxide production at a concentration of 40 µM, achieving an inhibition rate of over 50%. The compound also has an IC50 value of 2800 nM for its anti-inflammatory effect. Moreover, Rhodojaponin II exhibits low cytotoxicity, maintaining cell survival rates of 101.2% without LPS and 93.6% with LPS at a concentration of 200 µM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

1. Rhodojaponin II correlates pretty well with cardiotoxicity.

Chemical Properties

Molecular Weight	410.50
Formula	C₂₂H₃₄O₇
Cas No.	26116-89-2
Smiles	CC(=O)O[C@H]1C[C@@]23C[C@@](C)(O)[C@H](CC[C@H]2[C@](C)(O)[C@H]2[C@@H]4O[C@@H]4C(C)(C)[C@]12O)[C@@H]3O
Relative Density.	1.36 g/cm3 at 20℃

Storage & Solubility Information

Storage

In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

DMSO: 30.00 mg/mL (73.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4361 mL	12.1803 mL	24.3605 mL	121.8027 mL
5 mM	0.4872 mL	2.4361 mL	4.8721 mL	24.3605 mL
10 mM	0.2436 mL	1.2180 mL	2.4361 mL	12.1803 mL
20 mM	0.1218 mL	0.6090 mL	1.2180 mL	6.0901 mL
50 mM	0.0487 mL	0.2436 mL	0.4872 mL	2.4361 mL

Calculator

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc