Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,670.00 | |
50 mg | 6-8 weeks | $ 2,180.00 | |
100 mg | 6-8 weeks | $ 2,800.00 |
Description | PRMT4-IN-1 is a selective inhibitor of PRMT4, demonstrating an IC50 value of 3.2 nM, and has been shown to reduce the relative viability of MCF7 cells [1]. |
Targets&IC50 | PRMT1:0.835 μM, PRMT3:4.05 μM, PRMT4:3.2 nM, PRMT5:1.46 μM, PRMT6:1.75 μM, PRMT8:1.95 μM, PRMT7:1.68 μM |
In vitro | PRMT4-IN-1 (compound 12h) at concentrations of 10 μM, 50 μM, and 100 μM did not affect the number of metabolically active cells after exposure durations of 24 hours and 72 hours [1]. A time-dependent decrease in relative cell viability was observed in MCF7 cells treated with PRMT4-IN-1 (50 μM) over a period of 2-8 days [1]. |
Molecular Weight | 381.49 |
Formula | C23H28FN3O |
CAS No. | 912970-79-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PRMT4-IN-1 912970-79-7 Chromatin/Epigenetic Histone Methyltransferase CMPD 1 CMPD-1 PRMT4 IN 1 PRMT4IN1 inhibitor inhibit