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Anti-Alpha Actinin 2 Antibody (2O342)
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Catalog No. TMAC-00153
Alias sm Actinin-alpha, F-Actin Cross-Linking Protein, CMD1AA, alpha-SCA, alpha-actinin-2, alpha actinin skeletal muscle isoform 2, alpha actinin skeletal muscle, alpha actinin 2, ACTN2, ACTN 2, Actinin alpha 2, Actin binding protein
Anti-Alpha Actinin 2 Antibody (2O342) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (2O342) can be used in IHC,IP,WB.
Anti-Alpha Actinin 2 Antibody (2O342)
Anti-Alpha Actinin 2 Antibody (2O342)
😃Good
Catalog No. TMAC-00153Alias sm Actinin-alpha, F-Actin Cross-Linking Protein, CMD1AA, alpha-SCA, alpha-actinin-2, alpha actinin skeletal muscle isoform 2, alpha actinin skeletal muscle, alpha actinin 2, ACTN2, ACTN 2, Actinin alpha 2, Actin binding protein
Anti-Alpha Actinin 2 Antibody (2O342) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (2O342) can be used in IHC,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Alpha Actinin 2 Antibody (2O342) is a Rabbit antibody targeting Alpha Actinin 2. Anti-Alpha Actinin 2 Antibody (2O342) can be used in IHC,IP,WB. |
| Synonyms | sm Actinin-alpha, F-Actin Cross-Linking Protein, CMD1AA, alpha-SCA, alpha-actinin-2, alpha actinin skeletal muscle isoform 2, alpha actinin skeletal muscle, alpha actinin 2, ACTN2, ACTN 2, Actinin alpha 2, Actin binding protein |
| Ig Type | IgG |
| Clone | 2O342 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of ACTN2 on human heart lysates using anti-ACTN2 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat skeletal muscle tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse skeletal tissue using anti-ACTN2 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-ACTN2 antibody. Counter stained with hematoxylin.      |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The spectrin gene family encodes a diverse group of cytoskeletal proteins that include spectrins, dystrophins and α-actinins. There are four tissue-specific α-actinins, namely α-actinin-1, α-actinin-2, α-actinin-3 and α-actinin-4, which are localized to muscle and non-muscle cells, including skeletal, cardiac and smooth muscle cells, as well as within the cytoskeleton. Each α-actinin protein contains one Actin-binding domain, two calponin-homology domains, two EF-hand domains and four spectrin repeats, through which they function as bundling proteins that can cross-link F-Actin, thus anchoring Actin to a variety of intracellular structures. Defects in the gene encoding α-actinin-4 are the cause of focal segmental glomerulosclerosis 1 (FSGS1), a common renal lesion characterized by decreasing kidney function and, ultimately, renal failure. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 104 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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