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Mepyramine

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Catalog No. T24451Cas No. 91-84-9
Alias NSC-13136, NSC13136, NSC 13136

Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.

Mepyramine

Mepyramine

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Purity: 99.96%
Catalog No. T24451Alias NSC-13136, NSC13136, NSC 13136Cas No. 91-84-9
Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$62-In Stock
5 mg$138In StockIn Stock
10 mg$209In StockIn Stock
25 mg$333-In Stock
50 mg$475-In Stock
100 mg$638-In Stock
200 mg$853-In Stock
1 mL x 10 mM (in DMSO)$133-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.96%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Mepyramine is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies both parenterally and locally.
SynonymsNSC-13136, NSC13136, NSC 13136
Chemical Properties
Molecular Weight285.38
FormulaC17H23N3O
Cas No.91-84-9
SmilesN(CC1=CC=C(OC)C=C1)(CCN(C)C)C2=CC=CC=N2
Relative Density.1.0141 g/cm3 (Estimated)
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (192.73 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5041 mL17.5205 mL35.0410 mL175.2050 mL
5 mM0.7008 mL3.5041 mL7.0082 mL35.0410 mL
10 mM0.3504 mL1.7520 mL3.5041 mL17.5205 mL
20 mM0.1752 mL0.8760 mL1.7520 mL8.7602 mL
50 mM0.0701 mL0.3504 mL0.7008 mL3.5041 mL
100 mM0.0350 mL0.1752 mL0.3504 mL1.7520 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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