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Saponins

Name: Saponins
Brand: TargetMol
SKU: T6654
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T6654Cas No. 8047-15-2

Alias Sapogenins Glycosides

Saponins (Sapogenins Glycosides) are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effective for the treatment/prevention of venous insufficiency.

Saponins

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Catalog No. T6654Alias Sapogenins GlycosidesCas No. 8047-15-2

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$31	In Stock	In Stock
100 mg	$44	In Stock	In Stock
500 mg	$52	-	In Stock
1 g	$64	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Saponins (Sapogenins Glycosides) are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effective for the treatment/prevention of venous insufficiency.
In vitro	Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effective for the treatment/prevention of venous insufficiency. Sapogenins are the aglycones, or non-saccharide, portions of the family of natural products known as saponins. They may non-competitively inhibit hyaluronidase and elastase activities. [1]
Synonyms	Sapogenins Glycosides

Chemical Properties

Molecular Weight	1223.363
Formula	C₅₈H₉₄O₂₇
Cas No.	8047-15-2
Smiles	CC1(CCC23COC4(CCC5C6(C)CCC(OC7OCC(OC8OCC(O)C(O)C8O)C(OC8OC(CO)C(O)C(O)C8O)C7OC7OC(CO)C(O)C(O)C7OC7OC(CO)C(O)C(O)C7O)C(C)(C)C6CCC5(C)C4(C)CC2O)C3C1)C=O \|TLB:82:81:76.78.79:5.6\|
Relative Density.	1.218 g/cm3. Temperature:20.2 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 38.46 mg/mL (31.44 mM)

DMSO: Slightly soluble

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	0.8174 mL	4.0871 mL	8.1742 mL	40.8709 mL
5 mM	0.1635 mL	0.8174 mL	1.6348 mL	8.1742 mL
10 mM	0.0817 mL	0.4087 mL	0.8174 mL	4.0871 mL
20 mM	0.0409 mL	0.2044 mL	0.4087 mL	2.0435 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc