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Cytokine Receptor CD Proteins

Cytokines generally perform their biological functions by binding to the corresponding cytokine receptors on the cell surface. When a cytokine binds to its receptor, it initiates complex intracellular molecular interactions that ultimately lead to changes in cellular gene transcription. According to the structure of the cytokine receptor, it can be divided into different families or superfamilies, including immunoglobulin (Ig) superfamily, type I cytokine receptor, type II cytokine receptor, tumor necrosis factor receptor (TNFR) superfamily, and chemokine receptor.

FilterHomeRecombinant ProteinsCD ProteinsCytokine Receptor CD Proteins
  • IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)
    TMPJ-00239
    The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. Common IL2 receptor-γ Chain is also designated the common gamma chain.
    • $110
    7-10 days
    Size
    QTY
  • FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
    TMPJ-00391
    FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
    • $86
    7-10 days
    Size
    QTY
  • IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
    TMPJ-00291
    Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
    • $355
    7-10 days
    Size
    QTY
  • CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated
    TMPJ-00326
    Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
    • $355
    7-10 days
    Size
    QTY
  • CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
    TMPJ-00421
    CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
    • $47
    7-10 days
    Size
    QTY
  • IL-12RB1 Protein, Human, Recombinant (hFc)
    TMPJ-00363
    Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL12 with only low affinity. IL12 high affinity receptor complex is composed of two subunits designated IL12RB1 and IL12RB2. While IL12RB1 interacts with the IL-12p40 subunit, IL-12p35 is mainly connecting with IL12RB2. This receptor chain is also responsible for transmitting the IL12 signal into the cell. IL12RB1, to the contrary, is also part of the IL23R, where it interacts with the p40 subunit of IL23. IL12RB1 is expressed in activated T cells, NK cells and B cells.
    • $72
    7-10 days
    Size
    QTY
  • CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
    TMPJ-00343
    CD30/TNFRSF8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
    • $58
    7-10 days
    Size
    QTY
  • CD40 Protein, Cynomolgus, Recombinant (His)
    TMPJ-00634
    CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
    • $116
    7-10 days
    Size
    QTY
  • CXCR4 Protein, Human, Recombinant (hFc)
    TMPJ-01037
    C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T cells. CXCR4 stands out for its pleiotropic roles in both physiological and pathological conditions and it represents a crucial target in drug development. CXCL12 is the principal CXCR4 specific ligand and that the pro-inflammatory chemokine macrophage migration inhibitory factor (MIF) is also able to bind and activate CXCR4.
    • $138
    7-10 days
    Size
    QTY
  • IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi)
    TMPK-00164
    Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.6 kDa and the accession number is P01589.
    • $465
    7-10 days
    Size
    QTY
  • IL-18R alpha Protein, Human, Recombinant (His & Avi)
    TMPK-00316
    Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.8 kDa and the accession number is Q13478.
    • $207
    7-10 days
    Size
    QTY
  • M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)
    TMPK-00414
    M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 57.4 kDa and the accession number is P07333-1.
    • $231
    7-10 days
    Size
    QTY
  • PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00420
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is P16234.
    • $814
    7-10 days
    Size
    QTY
  • PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
    TMPK-00943
    Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF. PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.32 kDa and the accession number is Q0PW86.
    • $487
    7-10 days
    Size
    QTY
  • IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
    TMPK-00987
    The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling. IL-2 R gamma/CD132 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.2 kDa and the accession number is Q38JL2.
    • $814
    7-10 days
    Size
    QTY
  • FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
    TMPK-00847
    FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2.
    • $487
    7-10 days
    Size
    QTY
  • FGFR4 Protein, Human, Recombinant (His & Avi)
    TMPK-00379
    FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
    • $231
    7-10 days
    Size
    QTY
  • FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00380
    FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
    • $814
    7-10 days
    Size
    QTY
  • FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00381
    FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
    • $814
    7-10 days
    Size
    QTY
  • FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
    TMPK-00384
    FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
    • $347
    7-10 days
    Size
    QTY
  • FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
    TMPK-00392
    Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession number is P11362-7.
    • $347
    7-10 days
    Size
    QTY
  • FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00391
    Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.
    • $814
    7-10 days
    Size
    QTY
  • FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
    TMPK-00398
    FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
    • $534
    7-10 days
    Size
    QTY
  • FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00401
    Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
    • $814
    7-10 days
    Size
    QTY
  • PDGF R beta/CD140b Protein, Canine, Recombinant (His)
    TMPK-01050
    PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
    • $487
    7-10 days
    Size
    QTY
  • IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi)
    TMPK-00268
    Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5. IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.7 kDa and the accession number is Q01344-1.
    • $487
    7-10 days
    Size
    QTY
  • FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
    TMPK-00686
    FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9.
    • $418
    7-10 days
    Size
    QTY
  • IGF2R Protein, Human, Recombinant (His & Avi)
    TMPK-01354
    The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717.
    • $487
    In Stock
    Size
    QTY
  • gp130/IL6ST Protein, Human, Recombinant (hFc)
    TMPY-00387
    gp130/IL6ST Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 94.4 kDa and the accession number is AAA59155.1.
    • $165
    7-10 days
    Size
    QTY
  • IL-3R alpha/CD123 Protein, Mouse, Recombinant (His)
    TMPY-00592
    IL-3R alpha/CD123 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is EDL20630.1.
    • $600
    7-10 days
    Size
    QTY
  • Fas/CD95 Protein, Cynomolgus, Recombinant
    TMPY-00632
    Fas/CD95 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is F6V1W6.
    • $600
    7-10 days
    Size
    QTY
  • BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
    TMPY-00614
    BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is A0A8C0S7K5.
    • $398
    7-10 days
    Size
    QTY
  • FGFR4 Protein, Human, Recombinant (hFc)
    TMPY-00806
    FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1.
    • $600
    7-10 days
    Size
    QTY
  • BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
    TMPY-00962
    BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is P36895.
    • $700
    7-10 days
    Size
    QTY
  • LIFR Protein, Human, Recombinant (His)
    TMPY-00991
    LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1.
    • $386
    In Stock
    Size
    QTY
  • FGFR4 Protein, Mouse, Recombinant (His & hFc)
    TMPY-01019
    FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the accession number is A0A0R4IZY3.
    • $600
    7-10 days
    Size
    QTY
  • IL-4R Protein, Human, Recombinant (His)
    TMPY-01055
    IL-4R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.18 kDa and the accession number is P24394-1.
    • $451
    In Stock
    Size
    QTY
  • CD25/IL2R alpha Protein, Human, Recombinant (His)
    TMPY-01103
    CD25/IL2R alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01589.
    • $320
    In Stock
    Size
    QTY
  • PDGFRA Protein, Human, Recombinant (His)
    TMPY-01139
    PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1.
    • $386
    In Stock
    Size
    QTY
  • IL-6R Protein, Mouse, Recombinant (His)
    TMPY-01214
    IL-6R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P22272.
    • $386
    In Stock
    Size
    QTY
  • IL-7R alpha/CD127 Protein, Human, Recombinant (His)
    TMPY-01209
    IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
    • $451
    In Stock
    Size
    QTY
  • Fas/CD95 Protein, Mouse, Recombinant (His)
    TMPY-01426
    Fas/CD95 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is P25446.
    • $600
    7-10 days
    Size
    QTY
  • CD27/TNFRSF7 Protein, Mouse, Recombinant (His)
    TMPY-01432
    CD27/TNFRSF7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is P41272.
    • $700
    7-10 days
    Size
    QTY
  • IL-3R alpha/CD123 Protein, Human, Recombinant (His)
    TMPY-01410
    IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1.
    • $386
    In Stock
    Size
    QTY
  • CD27/TNFRSF7 Protein, Mouse, Recombinant (His & hFc)
    TMPY-01378
    CD27/TNFRSF7 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is P41272.
    • $700
    7-10 days
    Size
    QTY
  • IL-1R2 Protein, Rat, Recombinant (His)
    TMPY-02825
    IL-1R2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.7 kDa and the accession number is P43303.
    • $600
    7-10 days
    Size
    QTY
  • IL-2RG Protein, Rat, Recombinant (hFc)
    TMPY-02933
    IL-2RG Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 55 kDa and the accession number is Q68FU6.
    • $600
    7-10 days
    Size
    QTY
  • PDGFRB Protein, Rat, Recombinant (His)
    TMPY-03140
    PDGFRB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q05030.
    • $398
    7-10 days
    Size
    QTY
  • FGFR2 Protein, Mouse, Recombinant (His)
    TMPY-03389
    FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1.
    • $600
    7-10 days
    Size
    QTY
  • IL-4R Protein, Mouse, Recombinant (His)
    TMPY-02009
    IL-4R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P16382-1.
    • $361
    7-10 days
    Size
    QTY