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Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

(Synonyms: SIGLEC-15, Siglec15, HsT1361, CD33L3, CD33 molecule-like 3, CD33 antigen-like 3) Copy Product Info

Synonyms: SIGLEC-15, Siglec15, HsT1361, CD33L3, CD33 molecule-like 3, CD33 antigen-like 3

Catalog No. TMPK-00231 Copy Product Info
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.7 kDa and the accession number is A7E1W8-1.
Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1487-10 days7-10 days
20 µg$2457-10 days7-10 days
50 µg$4837-10 days7-10 days
100 µg$8137-10 days7-10 days
200 µg$1,4707-10 days7-10 days
500 µg$3,2507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.7 kDa and the accession number is A7E1W8-1.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberA7E1W8-1
ConstructionArg24-Thr262
Protein Purity
> 95% as determined by Tris-Bis PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 20 mM PB, 0.5M NaCl, 0.1M L-arginine (pH 7.4).
SynonymsSIGLEC-15, Siglec15, HsT1361, CD33L3, CD33 molecule-like 3, CD33 antigen-like 3
Research Background
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.
Chemical Properties
Molecular Weight26.7 kDa (predicted). Due to glycosylation, the protein migrates to 35-43 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated chemical structure | Siglec-15 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated molecular weight