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Anti-HTT Antibody (2P889)
(Synonyms: Huntington disease protein, Huntingtin, HD protein, HD IT15) Copy Product Info
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Synonyms: Huntington disease protein, Huntingtin, HD protein, HD IT15
Catalog No. TMAH-00585 Copy Product Info
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Anti-HTT Antibody (2P889) is an antibody targeting HTT. Anti-HTT Antibody (2P889) can be used in ELISA,IHC.
Anti-HTT Antibody
(2P889)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $209 | 7-10 days | 7-10 days | |
| 100 µL | $347 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-HTT Antibody (2P889) is an antibody targeting HTT. Anti-HTT Antibody (2P889) can be used in ELISA,IHC. |
| Synonyms | Huntington disease protein, Huntingtin, HD protein, HD IT15 |
| Ig Type | Rabbit IgG |
| Clone | 2P889 |
| Reactivity | Human |
| Verified Activity | 1. IHC image of TMAH-00585 diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. 2. IHC image of TMAH-00585 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | [Huntingtin]: Cytoplasm. Nucleus. Early endosome.; [Huntingtin, myristoylated N-terminal fragment]: Cytoplasmic vesicle, autophagosome. |
| Tissue Specificity | Expressed in the brain cortex (at protein level). Widely expressed with the highest level of expression in the brain (nerve fibers, varicosities, and nerve endings). In the brain, the regions where it can be mainly found are the cerebellar cortex, the neo |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | May play a role in microtubule-mediated transport or vesicle function. Promotes the formation of autophagic vesicles. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Huntingtin |
| Antigen Species | Human |
| Gene Name | HTT |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Neuroscience |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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