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Pralidoxime Iodide

Name: Pralidoxime Iodide
Brand: TargetMol
SKU: T22404
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22404Cas No. 94-63-3

Alias 2-PAM Iodide

Pralidoxime Iodide is an effective AChE reactivator and antidote for organophosphorus poisoning, reactivating AChE inhibited by nerve agents through nucleophilic attack on the phosphorus centre of the neurotoxin.

Pralidoxime Iodide

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Purity: 99.86%

Catalog No. T22404Alias 2-PAM IodideCas No. 94-63-3

Pack Size	Price	USA Warehouse	Global Warehouse
100 mg	$30	-	In Stock
500 mg	$55	-	In Stock
1 g	$79	-	In Stock
5 g	$193	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Pralidoxime Iodide is an effective AChE reactivator and antidote for organophosphorus poisoning, reactivating AChE inhibited by nerve agents through nucleophilic attack on the phosphorus centre of the neurotoxin.
In vivo	Pralidoxime Iodide (10-150 mg/kg, intramuscular injection, single dose) can reverse the respiratory toxicity induced by paraoxon in mice [3].
Synonyms	2-PAM Iodide

Chemical Properties

Molecular Weight	264.06
Formula	C₇H₉IN₂O
Cas No.	94-63-3
Smiles	[I-].ON=CC=1C=CC=C[N+]1C
Relative Density.	1.7439 g/cm3 (Estimated)

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (757.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7870 mL	18.9351 mL	37.8702 mL	189.3509 mL
5 mM	0.7574 mL	3.7870 mL	7.5740 mL	37.8702 mL
10 mM	0.3787 mL	1.8935 mL	3.7870 mL	18.9351 mL
20 mM	0.1894 mL	0.9468 mL	1.8935 mL	9.4675 mL
50 mM	0.0757 mL	0.3787 mL	0.7574 mL	3.7870 mL
100 mM	0.0379 mL	0.1894 mL	0.3787 mL	1.8935 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc