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Pralidoxime Iodide

Name: Pralidoxime Iodide
Brand: TargetMol
SKU: T22404
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22404Cas No. 94-63-3

Alias 2-PAM Iodide

Pralidoxime Iodide is an effective AChE reactivator and antidote for organophosphorus poisoning, reactivating AChE inhibited by nerve agents through nucleophilic attack on the phosphorus centre of the neurotoxin.

Pralidoxime Iodide

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Purity: 99.86%

Catalog No. T22404Alias 2-PAM IodideCas No. 94-63-3

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$30	-	In Stock
10 mg	$43	-	In Stock
25 mg	$72	-	In Stock
50 mg	$108	-	In Stock
100 mg	$162	-	In Stock
500 mg	$398	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Pralidoxime Iodide is an effective AChE reactivator and antidote for organophosphorus poisoning, reactivating AChE inhibited by nerve agents through nucleophilic attack on the phosphorus centre of the neurotoxin.
In vivo	Pralidoxime Iodide (10-150 mg/kg, intramuscular injection, single dose) can reverse the respiratory toxicity induced by paraoxon in mice [3].
Synonyms	2-PAM Iodide

Chemical Properties

Molecular Weight	264.06
Formula	C₇H₉IN₂O
Cas No.	94-63-3
Smiles	[I-].ON=CC=1C=CC=C[N+]1C
Relative Density.	1.7439 g/cm3 (Estimated)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (757.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7870 mL	18.9351 mL	37.8702 mL	189.3509 mL
5 mM	0.7574 mL	3.7870 mL	7.5740 mL	37.8702 mL
10 mM	0.3787 mL	1.8935 mL	3.7870 mL	18.9351 mL
20 mM	0.1894 mL	0.9468 mL	1.8935 mL	9.4675 mL
50 mM	0.0757 mL	0.3787 mL	0.7574 mL	3.7870 mL
100 mM	0.0379 mL	0.1894 mL	0.3787 mL	1.8935 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc