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CP-447697

Name: CP-447697
Brand: TargetMol
SKU: T60151
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60151Cas No. 1092847-21-6

CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.

CP-447697

🥰Excellent

Purity: 99.90%

Catalog No. T60151Cas No. 1092847-21-6

CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.

Pack Size	Price	Availability
5 mg	$45	In Stock
10 mg	$73	In Stock
25 mg	$157	In Stock
50 mg	$259	In Stock
100 mg	$387	In Stock

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Purity:99.90%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description

CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.

Chemical Properties

Molecular Weight	554.05
Formula	C₂₉H₂₆ClF₂N₃O₂S
Cas No.	1092847-21-6
Smiles	Fc1ccc(NC(=O)N2CCC(CC2)N(CCc2ccc(Cl)cc2)C(=O)c2csc3ccccc23)c(F)c1
Relative Density.	1.40 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 112.5 mg/mL (203.1 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8049 mL	9.0245 mL	18.0489 mL	90.2446 mL
5 mM	0.3610 mL	1.8049 mL	3.6098 mL	18.0489 mL
10 mM	0.1805 mL	0.9024 mL	1.8049 mL	9.0245 mL
20 mM	0.0902 mL	0.4512 mL	0.9024 mL	4.5122 mL
50 mM	0.0361 mL	0.1805 mL	0.3610 mL	1.8049 mL
100 mM	0.0180 mL	0.0902 mL	0.1805 mL	0.9024 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc