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Anti-SNAP-25 Antibody (5K558)

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Catalog No. TMAY-01916
Alias synaptosomal-associated protein, 25kDa, SNAP-25, SNAP, SEC9, RIC-4, RIC4, dJ1068F16.2, bA416N4.2

Anti-SNAP-25 Antibody (5K558) is a Rabbit antibody targeting SNAP-25. Anti-SNAP-25 Antibody (5K558) can be used in ELISA.

Anti-SNAP-25 Antibody (5K558)

Anti-SNAP-25 Antibody (5K558)

😃Good
Catalog No. TMAY-01916Alias synaptosomal-associated protein, 25kDa, SNAP-25, SNAP, SEC9, RIC-4, RIC4, dJ1068F16.2, bA416N4.2
Anti-SNAP-25 Antibody (5K558) is a Rabbit antibody targeting SNAP-25. Anti-SNAP-25 Antibody (5K558) can be used in ELISA.
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100 μL$270 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Rabbit Monoclonal

Application: ELISA

Reactivity: Human
Aliassynaptosomal-associated protein, 25kDa, SNAP-25, SNAP, SEC9, RIC-4, RIC4, dJ1068F16.2, bA416N4.2
Ig Type
Rabbit IgG
Clone
5K558
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human SNAP25 (rh SNAP25; TMPY-02245; P60880-1; Met1-Gly206).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSynaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the specificity of membrane fusion and to directly execute fusion by forming a tight complex that brings the synaptic vesicle and plasma membranes together. SNAP25 / SUP is a Q-SNARE protein contributing two α-helices in the formation of the exocytotic fusion complex in neurons where it assembles with syntaxin-1 and synaptobrevin. SNAP25 / SUP is involved in the molecular regulation of neurotransmitter release. It may play an important role in the synaptic function of specific neuronal systems. SNAP25 / SUP associates with proteins involved in vesicle docking and membrane fusion. SNAP25 / SUP regulates plasma membrane recycling through its interaction with CENPF. SNAP25 / SUP inhibits P/Q- and L-type voltage-gated calcium channels located presynaptically and interacts with the synaptotagmin C2B domain in Ca2+-independent fashion. In glutamatergic synapses SNAP25 / SUP decreases the Ca2+ responsiveness, while it is naturally absent in GABAergic synapses.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human SNAP25 protein (TMPY-02245)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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