INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 700.00 |
Description | INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features. |
Species | Human |
Expression System | HEK293 |
Tag | His |
Accession Number | Q9Y581 |
Synonyms | RIF1, insulin-like 6 |
Construction | A DNA sequence encoding the human INSL6 (NP_009110.2) (Met1-Phe198) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity | > 90 % as determined by SDS-PAGE. |
Molecular Weight | Approxiamtely 22.1 kDa |
Endotoxin | < 1.0 EU per μg protein as determined by the LAL method. |
Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Reconstitution | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | INSL6 (Insulin-Like 6) is a Protein Coding gene. An important paralog of this gene is RLN1. The protein encoded by this gene contains a classical signature of the insulin superfamily and is significantly similar to relaxin and relaxin-like factor. INSL6 is a newly identified insulin/relaxin family peptide hormone that is predominantly expressed by the male germ cells in testes. It may have a role in sperm development and fertilization. A recent murine study demonstrated that INSL6-knockout results in spermatogenic failure. Human and rat INSL6 encoded polypeptides of 213 and 188 amino acids, respectively. Diseases associated with INSL6 include Thrombocythemia 3 and Lymphoblastic Leukemia, Acute, With Lymphomatous Features. |
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INSL6 Protein, Human, Recombinant (His) RIF1 insulin-like 6 RIF-1 RIF 1 recombinant recombinant-proteins proteins protein