Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-gp130/IL6ST Antibody (1Y378) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (1Y378) can be used in ELISA,ELISA(Det).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $93 | 7-10 days | |
100 μL | $269 | 7-10 days |
Description | Anti-gp130/IL6ST Antibody (1Y378) is a Rabbit antibody targeting gp130/IL6ST. Anti-gp130/IL6ST Antibody (1Y378) can be used in ELISA,ELISA(Det). |
Alias | interleukin 6 signal transducer, IL-6RB, GP130, CDW130, CD130 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1Y378 |
Reactivity | Mouse |
Application | ELISA,ELISA(Det) |
Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse gp130 / CD130 / IL6ST (rM gp130 / CD130 / IL6ST; TMPY-01832; NP_034690.3; Met1-Glu617). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all cytokine receptors. CD130/gp130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and Oncostatin M (OSM). CD130/gp130 functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. CD130/gp130 plays a critical role in regulating myocyte apoptosis. Alternatively, spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1, and BSF3 can utilize gp130 for initiating signal transmission. CD130/gp130 binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. CD130/gp130 may have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events. |
Conjucates | Unconjugated |
Others Formats | HRP |
Antibody Types Available | 2 |
Immunogen | Recombinant Mouse gp130 / CD130 / IL6ST protein (TMPY-01832) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.