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Anti-PEDF Antibody (3M454)
😃Good
Catalog No. TMAY-01647
Alias serpin peptidase inhibitor, clade F，member 1, PIG35, PEDF, OI6, OI12, EPC-1
Anti-PEDF Antibody (3M454) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (3M454) can be used in ELISA.
Anti-PEDF Antibody (3M454)
Anti-PEDF Antibody (3M454)
😃Good
Catalog No. TMAY-01647Alias serpin peptidase inhibitor, clade F，member 1, PIG35, PEDF, OI6, OI12, EPC-1
Anti-PEDF Antibody (3M454) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (3M454) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-PEDF Antibody (3M454) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (3M454) can be used in ELISA. |
| Alias | serpin peptidase inhibitor, clade F，member 1, PIG35, PEDF, OI6, OI12, EPC-1 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 3M454 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PEDF / SerpinF1 (rh PEDF / SerpinF1; TMPY-01328; Met 1-Pro 418; NP_002606.3) . |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human PEDF / SerpinF1 Protein (TMPY-01328) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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