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Anti-FAP1 Antibody (6P590) (Synonyms: SIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE)

Catalog No. TMAC-01444 Copy Product Info
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Anti-FAP1 Antibody (6P590) is a Rabbit antibody targeting FAP1. Anti-FAP1 Antibody (6P590) can be used in IHC,WB.

Anti-FAP1 Antibody (6P590)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01444
Synonyms SIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE

Anti-FAP1 Antibody (6P590) is a Rabbit antibody targeting FAP1. Anti-FAP1 Antibody (6P590) can be used in IHC,WB.

Anti-FAP1 Antibody
(6P590)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FAP1 Antibody (6P590) is a Rabbit antibody targeting FAP1. Anti-FAP1 Antibody (6P590) can be used in IHC,WB.
SynonymsSIMP, Seprase, FAPα, FAPalpha, FAPA, FAP, DPPIVA, DPPIV, APCE
Ig Type
IgG
Clone
6P590
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-FAP1 antibody. Counter stained with hematoxylin.
verifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundFAP (fibroblast activation protein) is a cell surface glycoprotein and serine protease that is expressed primarily in fetal mesenchymal tissues and epithelial cancer fibroblasts. In cancer, FAP functions to promote cellular proliferation. In embryonic development, FAP functions to remodel developing tissues. FAP acts as an integral membrane gelatinase composed of N-glycosylated proteolytically inactive subunits. FAP expression on chondrocyte membranes is upregulated by the combination of the cytokines IL-1 and OSM and has been shown to increase in osteoarthritic patients. This expression is co-localized with MMP-1and MMP-13 as well as CD44 (variants v3 and v7/8). Mice that lack all copies of the FAP gene have been found to be fertile and to have developmental defects or change in cancer susceptibility.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 95 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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