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Anti-BDKRB1 Polyclonal Antibody
😃Good
Catalog No. TMAB-00204
Anti-BDKRB1 Polyclonal Antibody is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody can be used in WB.
Anti-BDKRB1 Polyclonal Antibody
Anti-BDKRB1 Polyclonal Antibody
😃Good
Catalog No. TMAB-00204
Anti-BDKRB1 Polyclonal Antibody is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-BDKRB1 Polyclonal Antibody is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Rabbit) |
| Verified Activity | 1. Sample: Lane 1: Human Siha cell lysates Lane 2: Human LOVO cell lysates Lane 3: Human K562 cell lysates Lane 4: Human A549 cell lysates Lane 5: Human Hela cell lysates Primary: Anti-BDKRB1 (TMAB-00204) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 60 kDa 2. Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Human SiHa cell lysates Lane 3: Human LOVO cell lysates Lane 4: Human K562 cell lysates Lane 5: Human U251 cell lysates Primary: Anti-BDKRB1 (TMAB-00204) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 60 kDa |
| Application | WB |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Kinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases. |
| Immunogen | KLH conjugated synthetic peptide: Human BDKRB1 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Macrophage / Inflamm.,Vitamins / minerals,Cancer,Vitamins / Minerals,Calcium Signaling,GPCR |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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