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Anti-BDKRB1 Polyclonal Antibody
(Synonyms: Bradykinin receptor B1, Bradykinin receptor 1, bradykinin B1R, Bradykinin B1 receptor, bradykinin B1 R, BRADYB1, BRADY B1, BKRB1, BKR1, BKR 1, BKB1R, BK-1 receptor, BDKRB1, BDKRB 1, BDKR B1, B1R, B1BKR, B1 bradykinin receptor) Copy Product Info
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Synonyms: Bradykinin receptor B1, Bradykinin receptor 1, bradykinin B1R, Bradykinin B1 receptor, bradykinin B1 R, BRADYB1, BRADY B1, BKRB1, BKR1, BKR 1, BKB1R, BK-1 receptor, BDKRB1, BDKRB 1, BDKR B1, B1R, B1BKR, B1 bradykinin receptor
Catalog No. TMAB-00204 Copy Product Info
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Anti-BDKRB1 Polyclonal Antibody is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody can be used in WB.
Anti-BDKRB1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-BDKRB1 Polyclonal Antibody is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody can be used in WB. |
| Synonyms | Bradykinin receptor B1, Bradykinin receptor 1, bradykinin B1R, Bradykinin B1 receptor, bradykinin B1 R, BRADYB1, BRADY B1, BKRB1, BKR1, BKR 1, BKB1R, BK-1 receptor, BDKRB1, BDKRB 1, BDKR B1, B1R, B1BKR, B1 bradykinin receptor |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Kinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases. |
| Immunogen | KLH conjugated synthetic peptide: Human BDKRB1 |
| Antigen Species | Human |
| Gene Name | BDKRB1 |
| Gene ID | |
| Protein Name | B1 bradykinin receptor |
| Uniprot ID | |
| Biology Area | Macrophage / Inflamm.,Vitamins / minerals,Cancer,Vitamins / Minerals,Calcium Signaling,GPCR |
| Function | This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation. |
| Molecular Weight | Theoretical: 40 kDa. Actual: 60 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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