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Synonyms: KCC2A, CaMK-II subunit alpha, CaMKII alpha, CaMKII, CAMKB, CAMKA, CAMK2α, CAMK2D, CAMK2B, CAMK2A, CAMK2 α, CaMK II delta subunit, CaMK II beta subunit, CaMK II alpha subunit, CaMK 2a, CAM2, CaM kinase II subunit alpha, CaM kinase II delta subunit, CaM kinase II delta chain, CaM kinase II beta subunit, CaM kinase II beta chain, CaM kinase II alpha subunit, CaM kinase II alpha chain, Calcium/calmodulin-dependent protein kinase(CaM kinase) II alpha, Calcium/calmodulin-dependent protein kinase type IIA, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/Calmodulin Dependent Protein Kinase II G, Calcium/calmodulin dependent protein kinase II alpha, Calcium calmodulin dependent protein kinase II alpha-B subunit, Calcium calmodulin dependent protein kinase II, Calcium calmodulin dependent protein kinase CaM kinase II alpha, alpha CaMKII
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-CAMK2 alpha Polyclonal Antibody 2 is a Rabbit antibody targeting CAMK2 alpha. Anti-CAMK2 alpha Polyclonal Antibody 2 can be used in ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | KCC2A, CaMK-II subunit alpha, CaMKII alpha, CaMKII, CAMKB, CAMKA, CAMK2α, CAMK2D, CAMK2B, CAMK2A, CAMK2 α, CaMK II delta subunit, CaMK II beta subunit, CaMK II alpha subunit, CaMK 2a, CAM2, CaM kinase II subunit alpha, CaM kinase II delta subunit, CaM kinase II delta chain, CaM kinase II beta subunit, CaM kinase II beta chain, CaM kinase II alpha subunit, CaM kinase II alpha chain, Calcium/calmodulin-dependent protein kinase(CaM kinase) II alpha, Calcium/calmodulin-dependent protein kinase type IIA, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/Calmodulin Dependent Protein Kinase II G, Calcium/calmodulin dependent protein kinase II alpha, Calcium calmodulin dependent protein kinase II alpha-B subunit, Calcium calmodulin dependent protein kinase II, Calcium calmodulin dependent protein kinase CaM kinase II alpha, alpha CaMKII |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse. Note=Postsynaptic lipid rafts. |
| Tissue Specificity | Widely expressed. Expressed in adult and fetal brain. Expression is slightly lower in fetal brain. Expressed in skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human CaMK2 alpha |
| Antigen Species | Human |
| Gene Name | CAMK2A |
| Gene ID | |
| Protein Name | Calcium/calmodulin-dependent protein kinase type II subunit alpha |
| Uniprot ID | |
| Biology Area | Calmodulin / CaMK,Hypoxia,Hypertrophy,Response to hypoxia |
| Function | CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. |
| Molecular Weight | Theoretical: 54 kDa. Actual: 54 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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