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Sodium 2-oxopropanoate

Name: Sodium 2-oxopropanoate
Brand: TargetMol
SKU: T7717
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7717Cas No. 113-24-6

Alias Sodium pyruvate

Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease.

Sodium 2-oxopropanoate

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Purity: 99.9%

Catalog No. T7717Alias Sodium pyruvateCas No. 113-24-6

Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 g	$31	-	In Stock

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Purity:99.9%

Color:White

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease.
In vivo	Sodium pyruvate nasal spray was effective in attenuating the rhinoconjunctivitis symptoms and reducing the rescue medication use of allergic rhinitis patients[1].
Animal Research	In the pollen season, all the participants were given corticosteroid nasal spray of standard dose for two weeks, and during the next two weeks they were randomized to treatment group (n = 23) taking nasal sodium pyruvate, and control group (n = 30) without sodium pyruvate.?Daily rhinoconjunctivitis symptom score and daily rescue medication score were analyzed.?Also the fraction of exhaled nitric oxide of the upper airway was measured before and after the treatment of sodium pyruvate[1].
Synonyms	Sodium pyruvate

Chemical Properties

Molecular Weight	110.0439
Formula	C₃H₃NaO₃
Cas No.	113-24-6
Smiles	CC(C(O[Na])=O)=O
Relative Density.	1.267g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 1.1 mg/mL (10 mM), Sonication is recommended.

H2O: 22.66 mg/mL (205.92 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	9.0873 mL	45.4364 mL	90.8728 mL	454.3641 mL
5 mM	1.8175 mL	9.0873 mL	18.1746 mL	90.8728 mL
10 mM	0.9087 mL	4.5436 mL	9.0873 mL	45.4364 mL

H2O

	1mg	5mg	10mg	50mg
20 mM	0.4544 mL	2.2718 mL	4.5436 mL	22.7182 mL
50 mM	0.1817 mL	0.9087 mL	1.8175 mL	9.0873 mL
100 mM	0.0909 mL	0.4544 mL	0.9087 mL	4.5436 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc