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Ethyl (triphenylphosphoranylidene) acetate

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Catalog No. T22329Cas No. 1099-45-2
Alias Triphenylcarbethoxymethylenephosphorane, Ethyl 2-(triphenylphosphoranylidene)acetate, (Carbethoxymethylene)triphenylphosphorane

Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.

Ethyl (triphenylphosphoranylidene) acetate

Ethyl (triphenylphosphoranylidene) acetate

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Purity: 97.98%
Catalog No. T22329Alias Triphenylcarbethoxymethylenephosphorane, Ethyl 2-(triphenylphosphoranylidene)acetate, (Carbethoxymethylene)triphenylphosphoraneCas No. 1099-45-2
Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 g$29-In Stock
1 mL x 10 mM (in DMSO)$29-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.98%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.
SynonymsTriphenylcarbethoxymethylenephosphorane, Ethyl 2-(triphenylphosphoranylidene)acetate, (Carbethoxymethylene)triphenylphosphorane
Chemical Properties
Molecular Weight348.37
FormulaC22H21O2P
Cas No.1099-45-2
SmilesCCOC(=O)C=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
Relative Density.1.086 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (157.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8705 mL14.3526 mL28.7051 mL143.5256 mL
5 mM0.5741 mL2.8705 mL5.7410 mL28.7051 mL
10 mM0.2871 mL1.4353 mL2.8705 mL14.3526 mL
20 mM0.1435 mL0.7176 mL1.4353 mL7.1763 mL
50 mM0.0574 mL0.2871 mL0.5741 mL2.8705 mL
100 mM0.0287 mL0.1435 mL0.2871 mL1.4353 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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