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PDL-1 cpd 10

🥰Excellent
Catalog No. T9359Cas No. 2767424-13-3

PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.

PDL-1 cpd 10

PDL-1 cpd 10

🥰Excellent
Purity: 97.08%
Catalog No. T9359Cas No. 2767424-13-3
PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50In StockIn Stock
5 mg$118In StockIn Stock
10 mg$189In StockIn Stock
25 mg$396In StockIn Stock
50 mg$587In StockIn Stock
100 mg$818In StockIn Stock
1 mL x 10 mM (in DMSO)$129In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:97.08%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.
Chemical Properties
Molecular Weight377.44
FormulaC21H23N5O2
Cas No.2767424-13-3
SmilesCC1=C(C=CC=C1COC=2N=C(NCCNC(C)=O)N=CN2)C3=CC=CC=C3
Relative Density.1.216 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (145.72 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.3 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6494 mL13.2471 mL26.4943 mL132.4714 mL
5 mM0.5299 mL2.6494 mL5.2989 mL26.4943 mL
10 mM0.2649 mL1.3247 mL2.6494 mL13.2471 mL
20 mM0.1325 mL0.6624 mL1.3247 mL6.6236 mL
50 mM0.0530 mL0.2649 mL0.5299 mL2.6494 mL
100 mM0.0265 mL0.1325 mL0.2649 mL1.3247 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PDL-1 cpd 10PDL1 cpd 10PD-L1PDL1PDL 1 cpd 10PD-1/PD-L1PD1/PDL1PD-1PD1
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