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Anti-CD16/FCGR3 Antibody-PE (4O520)
🥰Excellent
Catalog No. TMAY-03234P
Anti-CD16/FCGR3 Antibody-PE (4O520) is a PE-conjugated Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-PE (4O520) can be used in FCM.
Anti-CD16/FCGR3 Antibody-PE (4O520)
Anti-CD16/FCGR3 Antibody-PE (4O520)
🥰Excellent
Catalog No. TMAY-03234P
Anti-CD16/FCGR3 Antibody-PE (4O520) is a PE-conjugated Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-PE (4O520) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD16/FCGR3 Antibody-PE (4O520) is a PE-conjugated Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-PE (4O520) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4O520 |
| Reactivity | Mouse |
| Verified Activity | Flow cytometric analysis of Mouse FCGR3(CD16) expression on mouse splenocytes. BABL/c splenocytes were stained with PE-conjugated anti-Mouse FCGR3(CD16) and FITC-conjugated anti-Mouse CD3 (BD Pharmingen™ Cat. No. 553061). The dot plots were derived from events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD16 / FCGR3 (rM CD16 / FCGR3; TMPY-01834; P08508-1; Met1-Thr215) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
| Conjucates | PE |
| Others Formats | Unconjugated/APC/PerCP/FITC |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Mouse CD16 / FCGR3 protein (TMPY-01834) |
| Antigen Species | Mouse |
| Biology Area | Fc Receptors |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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