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Anti-CEACAM1 Antibody-APC (4V352)

🥰Excellent
Catalog No. TMAY-01218A

Anti-CEACAM1 Antibody-APC (4V352) is a APC-conjugated Rabbit antibody targeting CEACAM1. Anti-CEACAM1 Antibody-APC (4V352) can be used in FCM.

Anti-CEACAM1 Antibody-APC (4V352)

Anti-CEACAM1 Antibody-APC (4V352)

🥰Excellent
Catalog No. TMAY-01218A
Anti-CEACAM1 Antibody-APC (4V352) is a APC-conjugated Rabbit antibody targeting CEACAM1. Anti-CEACAM1 Antibody-APC (4V352) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CEACAM1 Antibody-APC (4V352) is a APC-conjugated Rabbit antibody targeting CEACAM1. Anti-CEACAM1 Antibody-APC (4V352) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
4V352
Reactivity
Human
Verified Activity
Flow cytometric analysis of anti-Human CEACAM1 on HT29 cells.
Application
FCM
Recommended Dose
2 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CEACAM1 / CD66a (rh CEACAM1 / CD66a; TMPY-00717; NP_001020083.1; Met1-Gly428) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundThe carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. CEACAM1, also known as biliary glycoprotein I (BGP I) and CD66a, is a member of the carcinoembryonic antigen (CEA) gene family which belongs to the immunoglobulin superfamily. The highly glycosylated CEACAM1 contains one N-terminal V-type Ig-like domain and three C2-type Ig-like domains within its ECD, and one ITIM motif and a calmodulin binding site in the cytoplasmic region. CEACAM1 is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells. It was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human CEACAM1 / CD66a protein (TMPY-00717)
Antigen Species
Human
Biology Area
Cancer Drug Targets, ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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