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CXCL4 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00012
Synonyms: PF-4, CXCL4, SCYB4, Oncostatin-A, MGC138298, Iroplact

Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes.

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CXCL4 Protein, Human, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 534.00
500 μg 5 days $ 2,140.00
1 mg 5 days $ 3,570.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes.
Species Human
Expression System E. coli
Tag N-His-Avi
Accession Number P02776
Synonyms PF-4, CXCL4, SCYB4, Oncostatin-A, MGC138298, Iroplact
Construction Recombinant Human CXCL4 Protein is expressed from E.coli with His tag and Avi tag at the N-Terminus. It contains Glu32-Ser101.[Accession |NP_002610.1]
Protein Purity > 95% as determined by Tris-Bis PAGE
Molecular Weight The protein has a predicted MW of 10.68 kDa same as Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in 4mM HCl. Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 4mM HCl.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes.

References and Literature

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Keywords

CXCL4 Protein, Human, Recombinant (His & Avi) MGC-138298 PF-4 CXCL4 MGC 138298 SCYB4 SCYB-4 SCYB 4 CXCL 4 Oncostatin-A PF4 MGC138298 CXCL-4 Iroplact PF 4 recombinant recombinant-proteins proteins protein

 

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