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CDAP

Name: CDAP
Brand: TargetMol
SKU: T65066
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T65066Cas No. 59016-56-7

Alias 1-Cyano-4-dimethylaminopyridinium tetrafluoroborate

CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.

CDAP

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Purity: 99.95%

Catalog No. T65066Alias 1-Cyano-4-dimethylaminopyridinium tetrafluoroborateCas No. 59016-56-7

CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
100 mg	$30	-	In Stock
200 mg	$42	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.
In vitro	The organic cyanating agent 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP) can be used to activate polysaccharides in water, which can then be reacted with hexamethylenediamine to prepare protein-polysaccharide conjugates. CDAP can be used to activate polysaccharides of different chemical natures, including dextran and pneumococcal types 6, 14, 19, and 23. [1]
Synonyms	1-Cyano-4-dimethylaminopyridinium tetrafluoroborate

Chemical Properties

Molecular Weight	234.99
Formula	C₈H₁₀BF₄N₃
Cas No.	59016-56-7
Smiles	N#C[N+]1=CC=C(N(C)C)C=C1.F[B-](F)(F)F

Storage & Solubility Information

Storage

store at low temperature | store at 4°C

Solubility Information

DMSO: 80 mg/mL (340.44 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.2555 mL	21.2775 mL	42.5550 mL	212.7750 mL
5 mM	0.8511 mL	4.2555 mL	8.5110 mL	42.5550 mL
10 mM	0.4256 mL	2.1278 mL	4.2555 mL	21.2775 mL
20 mM	0.2128 mL	1.0639 mL	2.1278 mL	10.6388 mL
50 mM	0.0851 mL	0.4256 mL	0.8511 mL	4.2555 mL
100 mM	0.0426 mL	0.2128 mL	0.4256 mL	2.1278 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc