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CDAP

🥰Excellent
Catalog No. T65066Cas No. 59016-56-7
Alias 1-Cyano-4-dimethylaminopyridinium tetrafluoroborate

CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.

CDAP

CDAP

🥰Excellent
Purity: 98.41%
Catalog No. T65066Alias 1-Cyano-4-dimethylaminopyridinium tetrafluoroborateCas No. 59016-56-7
CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$30-In Stock
200 mg$42-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.41%
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Product Introduction

Bioactivity
Description
CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.
In vitro
The organic cyanating agent 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP) can be used to activate polysaccharides in water, which can then be reacted with hexamethylenediamine to prepare protein-polysaccharide conjugates. CDAP can be used to activate polysaccharides of different chemical natures, including dextran and pneumococcal types 6, 14, 19, and 23. [1]
Synonyms1-Cyano-4-dimethylaminopyridinium tetrafluoroborate
Chemical Properties
Molecular Weight234.99
FormulaC8H10BF4N3
Cas No.59016-56-7
SmilesN#C[N+]1=CC=C(N(C)C)C=C1.F[B-](F)(F)F
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at 4°C
Solubility Information
DMSO: 80 mg/mL (340.44 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2555 mL21.2775 mL42.5550 mL212.7750 mL
5 mM0.8511 mL4.2555 mL8.5110 mL42.5550 mL
10 mM0.4256 mL2.1278 mL4.2555 mL21.2775 mL
20 mM0.2128 mL1.0639 mL2.1278 mL10.6388 mL
50 mM0.0851 mL0.4256 mL0.8511 mL4.2555 mL
100 mM0.0426 mL0.2128 mL0.4256 mL2.1278 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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