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CDAP

🥰Excellent
Catalog No. T65066Cas No. 59016-56-7
Alias 1-Cyano-4-dimethylaminopyridinium tetrafluoroborate

CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.

CDAP

CDAP

🥰Excellent
Purity: 98.41%
Catalog No. T65066Alias 1-Cyano-4-dimethylaminopyridinium tetrafluoroborateCas No. 59016-56-7
CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.
Pack SizePriceAvailabilityQuantity
100 mg$30In Stock
200 mg$42In Stock
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Purity:98.41%
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Product Introduction

Bioactivity
Description
CDAP is a cyanation reagent commonly used to modify protein thiols, and it can also be used to prepare protein-polysaccharide conjugates and activate polysaccharides in vaccine preparation.
In vitro
The organic cyanating agent 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP) can be used to activate polysaccharides in water, which can then be reacted with hexamethylenediamine to prepare protein-polysaccharide conjugates. CDAP can be used to activate polysaccharides of different chemical natures, including dextran and pneumococcal types 6, 14, 19, and 23. [1]
Alias1-Cyano-4-dimethylaminopyridinium tetrafluoroborate
Chemical Properties
Molecular Weight234.99
FormulaC8H10BF4N3
Cas No.59016-56-7
SmilesN#C[N+]1=CC=C(N(C)C)C=C1.F[B-](F)(F)F
Storage & Solubility Information
Storagestore at 4°C
Solubility Information
DMSO: 80 mg/mL (340.44 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.2555 mL21.2775 mL42.5550 mL212.7750 mL
5 mM0.8511 mL4.2555 mL8.5110 mL42.5550 mL
10 mM0.4256 mL2.1278 mL4.2555 mL21.2775 mL
20 mM0.2128 mL1.0639 mL2.1278 mL10.6388 mL
50 mM0.0851 mL0.4256 mL0.8511 mL4.2555 mL
100 mM0.0426 mL0.2128 mL0.4256 mL2.1278 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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