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Anti-BMAL1 Antibody (6E793)

(Synonyms: TIC, PASD3, PAS domain-containing protein 3, MOP3, Member of PAS protein 3, Class E basic helix-loop-helix protein 5(bHLHe5), Brain and muscle ARNT-like 1, BMAL1c, BMAL1, bHLH-PAS protein JAP3, BHLHE5, Basic-helix-loop-helix-PAS protein MOP3, Basic helix-loop-helix ARNT-like protein 1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, ARNTL1, ARNTL) Copy Product Info
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Synonyms: TIC, PASD3, PAS domain-containing protein 3, MOP3, Member of PAS protein 3, Class E basic helix-loop-helix protein 5(bHLHe5), Brain and muscle ARNT-like 1, BMAL1c, BMAL1, bHLH-PAS protein JAP3, BHLHE5, Basic-helix-loop-helix-PAS protein MOP3, Basic helix-loop-helix ARNT-like protein 1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, ARNTL1, ARNTL

Catalog No. TMAB-00239 Copy Product Info
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Anti-BMAL1 Antibody (6E793) is a Rabbit antibody targeting BMAL1. Anti-BMAL1 Antibody (6E793) can be used in FCM, WB.
Anti-BMAL1 Antibody
(6E793)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1547-10 days7-10 days
50 μL$2737-10 days7-10 days
100 μL$4897-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BMAL1 Antibody (6E793) is a Rabbit antibody targeting BMAL1. Anti-BMAL1 Antibody (6E793) can be used in FCM, WB.
SynonymsTIC, PASD3, PAS domain-containing protein 3, MOP3, Member of PAS protein 3, Class E basic helix-loop-helix protein 5(bHLHe5), Brain and muscle ARNT-like 1, BMAL1c, BMAL1, bHLH-PAS protein JAP3, BHLHE5, Basic-helix-loop-helix-PAS protein MOP3, Basic helix-loop-helix ARNT-like protein 1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, ARNTL1, ARNTL
Ig Type
IgG
Clone
6E793
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
FCM=1:50-100; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityHighly expressed in the adult brain, skeletal muscle and heart.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThe protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. The protein regulates interferon-stimulated gene expression and is an important factor in viral infection, including COVID-19. [provided by RefSeq, Oct 2021]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human BMAL1
Antigen Species
Human
Gene Name
BMAL1
Gene ID
Protein Name
Basic helix-loop-helix ARNT-like protein 1
Uniprot ID
Biology Area
Blood Pressure regulation,Cardiac metabolism,Cholesterol Metabolism,HLH,Transcription Factors,Cholesterol Metabolism,Metabolism
Function
ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.
Chemical Properties
Molecular WeightTheoretical: 69 kDa. Actual: 73-75 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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