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SCIN Protein, S. aureus, Recombinant (His & Myc)

(Synonyms: Staphylococcal complement inhibitor, scn, SCIN) Copy Product Info

Synonyms: Staphylococcal complement inhibitor, scn, SCIN

Catalog No. TMPH-03578 Copy Product Info
SCIN Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli. The accession number is A7X482.
SCIN Protein, S. aureus, Recombinant (His & Myc)
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Pack SizePriceEUR StockGlobal StockQuantity
5 µg116 €20 days20 days
10 µg194 €20 days20 days
20 µg324 €20 days20 days
50 µg488 €20 days20 days
100 µg670 €20 days20 days
200 µg963 €20 days20 days
500 µg1.557 €20 days20 days
1 mg2.277 €20 days20 days
For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
SCIN Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli. The accession number is A7X482.
Species
Staphylococcus aureus
Expression System
E. coli
TagN-10xHis, C-Myc
Accession NumberA7X482
Amino AcidSTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
Construction32-116 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsStaphylococcal complement inhibitor, scn, SCIN
Research Background
Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation. The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium. Also prevents C5a-induced neutrophil responses.
Chemical Properties
Molecular Weight17.2 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: SCIN Protein, S. aureus, Recombinant (His & Myc) chemical structure | SCIN Protein, S. aureus, Recombinant (His & Myc) molecular weight