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Lobaplatin

Name: Lobaplatin
Brand: TargetMol
SKU: T15771
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T15771Cas No. 135558-11-1

Alias D-19466

Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2]. It is a platinum complex with DNA alkylating activity.

Lobaplatin

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Purity: 99.96%

Catalog No. T15771Alias D-19466Cas No. 135558-11-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$89	-	In Stock
2 mg	$132	-	In Stock
5 mg	$226	-	In Stock
10 mg	$363	-	In Stock
1 mL x 10 mM (in H2O)	$248	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.96%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a promising antitumour chemotherapeutic agent[1][2]. It is a platinum complex with DNA alkylating activity.
Synonyms	D-19466

Chemical Properties

Molecular Weight	397.33
Formula	C₉H₁₈N₂O₃Pt
Cas No.	135558-11-1
Smiles	CC1[O-][Pt+2]2([NH2]CC3C(C[NH2]2)CC3)[O-]C1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 49 mg/mL (123.32 mM), DMSO inactivates the activity of obaplatin.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.5168 mL	12.5840 mL	25.1680 mL	125.8400 mL
5 mM	0.5034 mL	2.5168 mL	5.0336 mL	25.1680 mL
10 mM	0.2517 mL	1.2584 mL	2.5168 mL	12.5840 mL
20 mM	0.1258 mL	0.6292 mL	1.2584 mL	6.2920 mL
50 mM	0.0503 mL	0.2517 mL	0.5034 mL	2.5168 mL
100 mM	0.0252 mL	0.1258 mL	0.2517 mL	1.2584 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc