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CHL1 Protein, Human, Recombinant (His)

Catalog No. TMPY-01688
Synonyms: L1CAM2, cell adhesion molecule L1-like, CALL, LICAM2

CHL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 120 kDa and the accession number is AAI04919.1.

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CHL1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 600.00
500 μg 5 days $ 2,330.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description CHL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 120 kDa and the accession number is AAI04919.1.
Species Human
Expression System HEK293 Cells
Tag C-His
Accession Number AAI04919.1
Synonyms L1CAM2, cell adhesion molecule L1-like, CALL, LICAM2
Construction The extracellular domain of Human CHL1 (AAI04919.1) (Met 1-Gln 1080) was fused with a polyhistidine tag at the C-terminus.
Protein Purity > 95 % as determined by SDS-PAGE
Molecular Weight 120 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin type Ⅲ domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved in hemophilic disease.

References and Literature

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Keywords

CHL1 Protein, Human, Recombinant (His) L1CAM2 cell adhesion molecule L1-like LICAM-2 LICAM 2 CALL LICAM2 recombinant recombinant-proteins proteins protein

 

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