Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 465.00 | |
500 μg | 5 days | $ 1,850.00 | |
1 mg | 5 days | $ 3,100.00 |
Description | Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment. |
Species | Human |
Expression System | HEK293 |
Tag | C-hFc |
Accession Number | A0A024RC42 |
Synonyms | CDHN, Neural cadherin, CDH2, N-cadherin, CDw325, CD325, NCAD |
Construction | Recombinant Human N Cadherin Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Asp160-Ala724.[Accession |NP_001783.2] |
Protein Purity | > 90% as determined by Tris-Bis PAGE |
Molecular Weight | The protein has a predicted MW of 88.56 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment. |
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Please read the User Guide of Recombinant Proteins for more specific information.
N Cadherin Protein, Human, Recombinant (hFc) CD-325 CDH-2 CDHN Neural cadherin CDH2 N-cadherin CDw325 CDH 2 CD325 NCAD CD 325 recombinant recombinant-proteins proteins protein