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9(S)-HpOTrE

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Catalog No. T37867Cas No. 111004-08-1

9(S)-HpOTrE, a monohydroperoxy polyunsaturated fatty acid, is produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in 9,16-dihydroperoxy acid formation. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via the formation of an unstable epoxide.

9(S)-HpOTrE
Other Forms of 9(S)-HpOTrE:
13(S)-HpOTrET3739467597-26-6
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9(S)-HpOTrE

😃Good
Catalog No. T37867Cas No. 111004-08-1
9(S)-HpOTrE, a monohydroperoxy polyunsaturated fatty acid, is produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in 9,16-dihydroperoxy acid formation. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via the formation of an unstable epoxide.
Pack SizePriceAvailabilityQuantity
100 μg$39835 days
500 μg$1,56035 days
1 mg$2,73035 days
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Product Introduction

Bioactivity
Description
9(S)-HpOTrE, a monohydroperoxy polyunsaturated fatty acid, is produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in 9,16-dihydroperoxy acid formation. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via the formation of an unstable epoxide.
Chemical Properties
Molecular Weight310.434
FormulaC18H30O4
Cas No.111004-08-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: >50 mg/mL (from 13(S)-HODE), Sonication is recommended.
PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE), Sonication is recommended.
DMF: >50 mg/mL (from 13(S)-HODE), Sonication is recommended.
Ethanol: >50 mg/mL (from 13(S)-HODE), Sonication is recommended.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

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