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Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) can be used in ELISA,ICC/IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) can be used in ELISA,ICC/IF. |
Alias | UMPK, UMP-CMPK, UMK, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, CMPK, CMK, CK |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 3Z395 |
Reactivity | Human |
Verified Activity | Immunofluorescence staining of Human CMPK1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human CMPK1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green). Positive staining was localized to nucleus and cytoplasm. |
Application | ELISA,ICC/IF |
Recommended Dose | ELISA: 1:1000-1:2000; ICC-IF: 1:20-1:100 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CMPK1 (rh CMPK1; TMPY-04480; P30085; Met1-Gly196). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human CMPK1 protein (TMPY-04480) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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