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Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395)

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Catalog No. TMAY-02705
Alias UMPK, UMP-CMPK, UMK, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, CMPK, CMK, CK

Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) can be used in ELISA,ICC/IF.

Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395)

Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395)

😃Good
Catalog No. TMAY-02705Alias UMPK, UMP-CMPK, UMK, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, CMPK, CMK, CK
Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) can be used in ELISA,ICC/IF.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) is a Mouse antibody targeting UMP-CMP kinase/CMPK1. Anti-UMP-CMP kinase/CMPK1 Antibody (3Z395) can be used in ELISA,ICC/IF.
AliasUMPK, UMP-CMPK, UMK, cytidine monophosphate (UMP-CMP) kinase 1, cytosolic, CMPK, CMK, CK
Ig Type
Monoclonal Mouse IgG1
Clone
3Z395
Reactivity
Human
Verified Activity
Immunofluorescence staining of Human CMPK1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human CMPK1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green). Positive staining was localized to nucleus and cytoplasm.
Application
ELISA,ICC/IF
Recommended Dose
ELISA: 1:1000-1:2000; ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CMPK1 (rh CMPK1; TMPY-04480; P30085; Met1-Gly196). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CMPK1 protein (TMPY-04480)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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