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Anti-Phospho-TERT (Ser227) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TERT (Ser227). Anti-Phospho-TERT (Ser227) Polyclonal Antibody can be used in ICC/IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $316 | 7-10 days |
Description | Anti-Phospho-TERT (Ser227) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TERT (Ser227). Anti-Phospho-TERT (Ser227) Polyclonal Antibody can be used in ICC/IF,ELISA. |
Ig Type | IgG |
Reactivity | Human |
Application | |
Recommended Dose | ICC/IF: 1:200-1000; ELISA: 1:10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | telomerase reverse transcriptase(TERT) Homo sapiens Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative sp |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human Telomerase around the phosphorylation site of Ser227. AA range:196-245 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 126 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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