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Carpaine is a natural product exhibiting antimalarial activity, with an approximate IC50 of 4μM against P. falciparum in NL20 cells. It demonstrates cardioprotective and anti-inflammatory effects by activating FAK, ERK1/2, and AKT pathways while inhibiting ROS production.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $183 | - | In Stock | |
| 5 mg | $453 | - | In Stock | |
| 10 mg | $668 | - | In Stock | |
| 25 mg | $1,050 | - | In Stock | |
| 50 mg | $1,420 | - | In Stock |
| Description | Carpaine is a natural product exhibiting antimalarial activity, with an approximate IC50 of 4μM against P. falciparum in NL20 cells. It demonstrates cardioprotective and anti-inflammatory effects by activating FAK, ERK1/2, and AKT pathways while inhibiting ROS production. |
| In vivo | Circulatory effects of Carpaine were studied in Wistar male rats weighing 314 +/- 13 g, under pentabarbital (30 mg/kg) anesthesia. Increasing dosages of Carpaine from 0.5 mg/kg to 2.0 mg/kg resulted in progressive decrease in systolic, diastolic, and mean arterial blood pressure[3]. |
| Molecular Weight | 478.71 |
| Formula | C28H50N2O4 |
| Cas No. | 3463-92-1 |
| Smiles | C[C@H]1[C@@]2(CC[C@](N1)(CCCCCCCC(=O)O[C@@]3([C@H](C)N[C@](CCCCCCCC(=O)O2)(CC3)[H])[H])[H])[H] |
| Relative Density. | 1.0566 g/cm3 (Estimated) |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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