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Anti-Phospho-MAPT (Ser202) Antibody (2U827)

😃Good
Catalog No. TMAH-00921
Alias TAU and MAPT, p-MAPT (Ser202), p-MAPT (S202), Phospho-MAPT (S202), Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL, MAPT (p-Ser202), MAPT (p-S202)

Anti-Phospho-MAPT (Ser202) Antibody (2U827) is an antibody targeting Phospho-MAPT (Ser202). Anti-Phospho-MAPT (Ser202) Antibody (2U827) can be used in ELISA, FCM.

Anti-Phospho-MAPT (Ser202) Antibody (2U827)

Anti-Phospho-MAPT (Ser202) Antibody (2U827)

😃Good
Catalog No. TMAH-00921Alias TAU and MAPT, p-MAPT (Ser202), p-MAPT (S202), Phospho-MAPT (S202), Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL, MAPT (p-Ser202), MAPT (p-S202)
Anti-Phospho-MAPT (Ser202) Antibody (2U827) is an antibody targeting Phospho-MAPT (Ser202). Anti-Phospho-MAPT (Ser202) Antibody (2U827) can be used in ELISA, FCM.
Pack SizePriceAvailabilityQuantity
50 μL$207 7-10 days
100 μL$347 7-10 days
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Product Introduction

Bioactivity
Description
Antibody Type: Recombinant Rabbit Monoclonal

Application: ELISA, FCM

Reactivity: Human
AliasTAU and MAPT, p-MAPT (Ser202), p-MAPT (S202), Phospho-MAPT (S202), Paired helical filament-tau, Neurofibrillary tangle protein, MTBT1, Microtubule-associated protein tau, MAPTL, MAPT (p-Ser202), MAPT (p-S202)
Ig Type
Rabbit IgG
Clone
2U827
Reactivity
Human
Verified Activity
Overlay Peak curve showing SH-SY5Y cells stained with TMAH-00921 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed.
Application
ELISA, FCM
Recommended Dose
FCM:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationCytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundPromotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human MAPT
Antigen Species
Human
Gene ID
4137
Uniprot ID
Biology Area
Neuroscience, Signal transduction
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Sci Citations

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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