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Anti-Transferrin Receptor/TFRC Antibody (1W119)

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Catalog No. TMAY-03442
Alias transferrin receptor

Anti-Transferrin Receptor/TFRC Antibody (1W119) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (1W119) can be used in IHC-P.

Anti-Transferrin Receptor/TFRC Antibody (1W119)

Anti-Transferrin Receptor/TFRC Antibody (1W119)

😃Good
Catalog No. TMAY-03442Alias transferrin receptor
Anti-Transferrin Receptor/TFRC Antibody (1W119) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (1W119) can be used in IHC-P.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Transferrin Receptor/TFRC Antibody (1W119) is a Rabbit antibody targeting Transferrin Receptor/TFRC. Anti-Transferrin Receptor/TFRC Antibody (1W119) can be used in IHC-P.
Aliastransferrin receptor
Ig Type
Monoclonal Rabbit IgG
Clone
1W119
Reactivity
Mouse
Verified Activity
1. Immunochemical staining of mouse TFRC in mouse liver with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

2. Immunochemical staining of mouse TFRC in mouse kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.

3. Immunochemical staining of mouse TFRC in mouse small intestine with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections.
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Transferrin Receptor / TFRC (rM Transferrin Receptor / TFRC; TMPY-02294; Q62351; Cys89-Phe763).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundTransferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse Transferrin Receptor / TFRC Protein (TMPY-02294)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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